The 42-year-old actress, who plays Amy Fowler on the CBS sitcom, dedicated a sweet message on Instagram to Parsons, who portrays Amy's fiancé, Sheldon Cooper.
Bialik shared a photo of herself and Parsons posing in a car on the Big Bang Theory set. The show returned for a 11th season on CBS in September, and airs new episodes Thursdays.
"If Amy could, she'd make Sheldon Cooper her #ManCrushMonday so I'll do it for her and say that every day that I get to work with @therealjimparsons is a great day! You're my #MCM, Jim!" Bialik wrote.
Thursday's episode followed Amy and Sheldon as they planned their upcoming wedding. Showrunner Steve Holland teased the nuptials in an interview with The Hollywood Reporter published in September.
"It's not going to be super quick; there are certainly fun stories to play with this couple planning their wedding," the producer said. "Specifically, Sheldon, who has ideas about everything, is going to have ideas about their wedding."
"[He's a bridezilla] but in a sweet way, where he wants it to be perfect," he added. "So Amy has to love that he's doing that but also be frustrated by it."