Kimmel will be absent from his late night show throughout the week as his son's heart surgery was delayed due to a cold.
"As a precautionary measure, the scheduled second heart surgery for Jimmy Kimmel's son Billy had to be postponed this week due to the common cold," a representative for the show said Monday. "Jimmy is very grateful to Shaquille O'Neal, Dave Grohl, Channing Tatum and Jennifer Lawrence for filling his very small shoes as guest host this week while he, his wife and children sneeze on each other."
Lawrence will be hosting Thursday with guest Kim Kardashian and musical performers Linkin Bridge.
Kimmel is expected to return to hosting next week.