Also expected to take part in the fundraiser are Zach Galifianakis, Matt Bomer, Dave Franco, Sonequa Martin-Green, Rob Riggle, Tony Hale, Terry Crews, Mel B and Bree Turner.
The celebrities have been added to a roster of previously announced stars that includes Ben Affleck, Matthew McConaughey, Emma Stone, Anna Kendrick, Josh Gad, Niecy Nash, Eric Stonestreet, Alison Sweeney, Ken Jeong, Marcia Cross, Greg Grunberg, Danielle Campbell, Charlie Wilson, Brittany Daniel and SU2C co-founder Katie Couric. Among the special's musical performers will be Celine Dion, Dierks Bentley, Keith Urban and Little Big Town.
Bradley Cooper, actor and founder of the Bradley Charles Cooper Foundation, will executive-produce the program alongside Done + Dusted, in collaboration with Stand Up to Cancer's production team.
"It's truly inspiring to see so many people come together for this cause," Couric said in a statement. "We have a great show lined up this year and are grateful to the amazing individuals taking time out of their schedules to participate. It will be a fantastic opportunity for people to learn about some of the incredible new breakthroughs in cancer research and treatment that are giving real hope to many patients and their loved ones."
The telecast will air live from The Music Center's Walt Disney Concert Hall in downtown Los Angeles.
ABC, CBS, FOX and NBC, as well as American Forces Network, ASPiRE, AUDIENCE Network, Bloomberg TV, Bravo, Comedy Central, Discovery Life, E! Entertainment, EPIX, ESPNEWS, FM, FS2, Fusion, FXM, Great American Country, HBO, HLN, ION Television, LMN, Logo, MLB Network, National Geographic, Pivot, RLTV, SHOWTIME, Smithsonian Channel, STARZ, STARZ ENCORE, TBS, Tr3s, VH1 and WGN America are donating one hour of simultaneous, commercial-free, primetime for the telecast.