Updated: Sept. 21, 2018 at 7:04 AM

'Will & Grace' turns 20: The cast through the years (69 images)

The first episode of "Will & Grace" aired 20 years ago on September 21, 1998. Here's a look back at the cast through the years.

Messing, the voice of Beth in "Open Season," arrives with her husband, Daniel Zelman, for the the premiere of the film in Los Angeles on September 25, 2006. File Photo by Jim Ruymen/UPI

License photo | Permalink

William Shatner (L) and Messing present the award for Outstanding Lead Actress in a Comedy Series during the 59th Primetime Emmy Awards in Los Angeles on September 16, 2007. File Photo by Jim Ruymen/UPI

License photo | Permalink

From left to right, Shuler Hensley, Mullally and Roger Bart take their opening night curtain call bows for the Broadway musical "Young Frankenstein" on November 8, 2007. File Photo by Ezio Petersen/UPI

License photo | Permalink

Messing attends the NBC All-Star party in Beverly Hills, Calif., on July 20, 2008. File Photo by Jim Ruymen/UPI

License photo | Permalink