The clip, released on Wednesday, features Foxx's character Joe Gardner playing the piano and asking the audience what they want to be remembered for in their lives.
Gardner, after scoring a jazz gig, falls into a sewer while walking around New York City where he finds himself entering into a fantastical world.
"In the film, just when Joe thinks his dream might be in reach, a single unexpected step sends him to a fantastical place where he's forced to think again about what it truly means to have soul," reads the synopsis.
Soul, from director Pete Docter and co-directed by Kemp Powers, will arrive in theaters on June 19. Questlove, Daveed Diggs and Phylicia Rashad will also provide voices.