The clip, released Wednesday, features Keaton as entrepreneur V.A. Vandevere who wants to use Dumbo for a new entertainment venture called Dreamland.
"You have something very rare. You have wonder. You have mystique. You have magic," Keaton says to circus leader Max Medici, portrayed by Danny DeVito. "Together we can soar on that elephant's wings."
Colin Farrell, as circus handler Holt Farrier, also appears alongside his children, played by Nico Parker and Finley Hobbins. The family cares for Dumbo and take action to save their flying elephant from being exploited.
Dumbo, from director Tim Burton, is set to arrive in theaters on March 29.