Clooney, a double Oscar winner, will be honored June 7 at the 46th AFI Life Achievement Award Gala Tribute at the Dolby Theatre in Hollywood. The event is scheduled to air on TNT June 21.
Roberts, 50, and Clooney, 57, have shared the screen in Ocean's 11, Ocean's 12 and Money Monster. He directed her in Confessions of a Dangerous Mind and produced her film August: Osage County.
Clooney's other movies include Suburbicon, Gravity, Syriana, Michael Clayton, Up in the Air, Good Night, and Good Luck, O Brother, Where Art Thou?, Batman and Robin, and One Fine Day. He also was a cast member of the television medical drama ER.