The Late Night with Seth Meyers host discussed SNL on Tuesday's episode of Watch What Happens Live after Louis-Dreyfus said her time on the show was a "miserable" experience.
Meyers was a cast member and writer for SNL from 2001 to 2014, while Louis-Dreyfus appeared on the series from 1982 to 1985. Meyers told WWHL host Andy Cohen he wasn't aware of Louis-Dreyfus' comments.
"I don't know the statement, but I would say that we worked there during very different eras," Meyers said. "I know Julia was there in the '80s.
"I think I worked there at a much better time. I think part of that was, when I started on the show, Tina Fey was head writer and there were a lot of strong women at the show who were in positions of power. I think they laid out a much better framework for that not to be an issue," he explained. "So I was lucky in the time I worked there."
"I was incredibly naive," the actress said. "I didn't understand how the dynamics of the place worked. It was very, very sexist. People were doing crazy drugs. I was oblivious; I just thought, 'Oh, wow, he's got a lot of energy.'"
Louis-Dreyfus said meeting Seinfeld creator Larry David was a silver lining to the "brutal" experience.
"We bonded because he was as miserable as I was. He would write these sketches and they would not see the light of day. I would go into his office and cry a lot," she said.