Us Weekly reported the 25-year-old singer purged nearly 300 people from her account Saturday and is now following just 37 accounts.
Gomez unfollowed Lovato, Hadid, Camila Cabello, her Wizards of Waverly Place co-stars, the 13 Reasons Why cast and other friends and former co-stars, causing fans to speak out about the change.
"Damn, Selena has unfollowed a lot of people on Instagram," one fan account tweeted.
Gomez is still following Taylor Swift, Francia Raisa, Amy Schumer, Jessica Alba and a handful of other friends and fan accounts. She last posted a photo of herself outside her childhood home the same day as her Instagram purge.
"The home I grew up in, from birth to 13... (no one was home when I knocked this time lol) I visit this place every chance I get," the star wrote.
The home I grew up in, from birth to 13... (no one was home when I knocked this time lol) I visit this place every chance I get. In many ways it very well could have been better than my life today, but I’m grateful for a voice that can enable change today. Even when I don’t know how to do it well or actually want it. I love you Grand Prairie. Thank you. ❤️
Gomez made headlines in November after she unfollowed her ex-boyfriend, singer The Weeknd, after their split. She has since been linked to her ex-boyfriend Justin Bieber, and was spotted with the singer at a pilates class Jan. 3.