"He could end this," the former King of Queens star said about Cruise's celebrity, and the power that it gives him within the church, referring to leaders of the Church of Scientology talking about Cruise as an actor who is "clearing the planet" and "changing the planet."
"Changing the planet? He couldn't even make Jack Reacher a hit," Maher said, jokingly.
Remini also shared how followers of Scientology are expected to study the religion for at least two hours every day.
"We are looking up the words, we are being checked out on the policies of Scientology."
When asked if Cruise is expected to do the same, Remini confirmed he was but noted, "I don't want you to get the idea that he's not, that certain policies are not being bent for him because they are and that is the truth, and that is part of the hypocrisy."
Remini's appearance on the talk show comes after the actress released a book in 2016 called Troublemaker: Surviving Hollywood and Scientology and an A&E documentary series titled Leah Remini: Scientology and the Aftermath about her experiences with the religion.
Cruise broke his normally public silence on Scientology on the red carpet for his latest film Jack Reacher: Never Go Back stating, "It's something that has helped me incredibly in my life."
"It's something, you know, without it, I wouldn't be where I am... I'm incredibly proud," he continued.
"He honestly believes ... Tom and most Scientologists, all Scientologists, are taught to believe that people like me are literally the devil, that we mean them harm," she continued.