"I hope everybody votes. I know it's a tough decision," the comedian joked onstage according to Spin before digging into the real estate mogul.
"Hillary Clinton vs. white Malcolm X. That crazy character, [expletive] is gonna kill us all. And lower my taxes," he continued.
Chappelle also threw a couple of comedic shots towards fellow comics Keegan-Michael Key and Jordan Peele for their Comedy Central series Key and Peele whom Chappelle compared to his own former program, Chappelle's Show.
"Put some respect on my name. Y'all don't know what I've been through, watching Key & Peele do my show the last five [expletive] years," he said before comparing himself to Morgan Freeman due to his old age.