According to Us Weekly, the couple decided to go their separate ways six months ago. They have two children together, Noah, 2, and Bodhi, 18 months. Before the split, they had been linked for at least 11 years.
Fox, 29, and Green, 42, were last seen together in June, the outlet reports. They married in 2010, days after a second proposal.
"I've never been more sure of anything in my life," Green reportedly said at the time of his Hawaiian wedding to Fox, then 23. "It was the absolute perfect start to what we hope will be an amazing life together.
According to reports, the entertainers first met on set of Hope & Faith in 2004.