The advert sees the 39-year-old actress, Kevin Smith, Jason Mewes and Michael Rooker attend a cameo school taught by the 92-year-old former Marvel president. Smith also directed the video.
Lee is well known for making unassuming cameos in Marvel films and other projects, including his brief appearance as a security guard in Captain America: The Winter Soldier. The promo itself features a cameo by Lou Ferrigno.
Lee is expected to cameo in Avengers: Age of Ultron, which opens in theaters Friday. The sequel will see Iron Man (Robert Downey, Jr.), Black Widow (Scarlett Johansson), Captain America (Chris Evans) and the rest of the team take on the supervillain Ultron (James Spader).