During his opening remarks, the Oscar and Grammy winning actor and musician poked fun at Jenner's alleged transition from male to female telling the audience the former Olympian would be performing "a his-and-her duet all by himself." When the audience cracked up in laughter, Foxx explained he was only joking.
"Look, I'm just busting your balls while I still can," he said to more laughs.
But while some event attendees were seen laughing out loud at the comments, the Internet had a different reaction to the remarks.
".@iamjamiefoxx making transphobic jokes at Bruce Jenner's expense while Kylie is in the audience? Grow up & educate yourself. #iHeartAwards," wrote Twitter user @LuigiM227.