In a clip of the show posted Saturday, Kutcher tells DeGeneres he has just been pitched the final episode and admits he's probably not allowed to talk about it.
When DeGeneres asks if Sheen will appear on the finale, the 36-year-old actor makes an incredibly awkward face that promptly leads the host to affirm that, Sheen will be back.
"I didn't say anything," responded Kutcher, before adding, "If you're working in the Warner Brothers lot and there's sirens come save me."
DeGeneres predictions are not as far fetched as they might seen as Sheen told TV Guide in September that he reached out to series creator Chuck Lorre about his character Charlie Harper returning for the series finale.
Sheen, 49, was fired from Men in 2011 after eight seasons on the show.
The Two and a Half Men finale will air on Feb. 19.