Valerie Elise Plame Wilson (born 19 April 1963), known as Valerie Plame, Valerie E. Wilson, and Valerie Plame Wilson, and the wife of former Ambassador Joseph C. Wilson, IV, is a former United States CIA Operations Officer.

Valerie Elise Plame was born on April 19, 1963, on Elmendorf Air Force Base, in Anchorage, Alaska, to Diane and Samuel Plame. Plame's paternal great-grandfather was a rabbi who emigrated from Ukraine; the original family surname was "Plamevotski" (Wilson, Fair Game 173).

Growing up in "a military family ... imbued her with a sense of public duty"; her father was a lieutenant colonel in the United States Air Force, who worked for the National Security Agency for three years, and, according to her "close friend Janet Angstadt," her parents "are the type who are still volunteering for the Red Cross and Meals on Wheels in the Philadelphia suburb where they live," having moved to that area while Plame was still in school.