Susan G. Komen for the Cure, formerly known as The Susan G. Komen Breast Cancer Foundation, often referred to as simply Komen, is an organization supporting breast cancer research. Since its inception in 1982, Komen has raised over $1.3 billion for research, education and health services, making it the largest breast cancer charity in the world. Today, the Komen organization is recognized as the leading catalyst in the fight against breast cancer, with more than 100,000 volunteers working in a network of 125 U.S. and international affiliates. Susan G. Komen for the Cure received Charity Navigator's highest rating, four stars.

Susan Goodman Komen was born October 31, 1943 in Peoria, Illinois, and was diagnosed with breast cancer at the age of 33 and died three years later, in 1980. Komen's younger sister, Nancy Goodman Brinker, who felt that Susan's outcome might have been better if patients knew more about cancer and its treatment, and remembering a promise to her sister that she would find a way to speed up breast cancer research, founded the Susan G. Komen Breast Cancer Foundation in Komen's memory in 1982.

In 2007, the 25th anniversary of the organization, it changed its name to Susan G. Komen for the Cure, created a new logo, and adopted the explicit mission "to end breast cancer forever".