Preston Burpo (born September 26, 1972, in Bethesda, Maryland) is an American soccer player who currently plays for Colorado Rapids in Major League Soccer.

Burpo played collegiate soccer at Southern New Hampshire University from 1992 to 1995. During his career there he earned a goals against average of 1.19 and recorded 38 shutouts. He was the first Penman to earn All-Region honors in 1992.

Upon graduating in 1995 he had brief stints with the New Hampshire Phantoms and the Boston Storm of the USISL, and also played briefly with the Jamaican club team Harbor View FC. In 1997 he signed with the Seattle Sounders of the USL First Division where he would play for the next nine years. During his career with the Sounders, Burpo appeared 143 times, notching 38 shutouts, 631 saves, and a GAA of 1.19 along the way.