Michigan company to upgrade Army's Bradley Fighting Vehicles

Michigan company to upgrade Army's Bradley Fighting Vehicles

PLYMOUTH, Mich., July 31 (UPI) --A small Michigan business has won a major contract from the U.S. Army to restore and upgrade the mobility capabilities of Bradley Fighting Vehicles.
Richard Tomkins
Wood Group lands Shah Deniz gas contract

Wood Group lands Shah Deniz gas contract

ABERDEEN, Scotland, June 3 (UPI) --Scottish engineering company Wood Group Kenny said Tuesday it landed a $60.2 million contract from BP to develop gas reserves off the coast of Azerbaijan.
Daniel J. Graeber
Oil services group Expro lands Shah Deniz contract

Oil services group Expro lands Shah Deniz contract

READING, England, April 23 (UPI) -- Oilfield services company Expro said Wednesday it won a contract to help BP develop Phase II of the Shah Deniz gas field in the Azeri waters of the Caspian Sea.
Daniel J. Graeber

Baku creates entity to manage Shah Deniz

BAKU, Azerbaijan, Feb. 26 (UPI) -- The government of Azerbaijan announced it established a company to manage Phase II of the Shah Deniz gas field in the Caspian Sea and its associated pipelines.

UPI Thoroughbred Racing Roundup

Wrap-up of thoroughbred stakes action.

SCRA providing management support to Navy programs

CHARLESTON, S.C., Jan. 23 (UPI) -- Program management support for U.S. Navy small business programs is to be provided by SCRA Applied R&D under an $857,394 task order.

DARPA taps NovaWurks for satellite component repurposing

LOS ALAMITOS, Calif., Jan. 8 (UPI) -- Space technology firm NovaWurks Inc. has received a U.S. military contract to repurpose components from non-working satellites still in orbit.
Loc Performance continues Army work

Loc Performance continues Army work

PLYMOUTH, Mich., Nov. 8 (UPI) -- The U.S. Army has given Loc Performance Products Inc. a Phase II contract for modernization of the drive system of Bradley fighting vehicles.

Phase 2 of India's solar mission faces delays

NEW DELHI, Sept. 17 (UPI) -- India's solar sector is awaiting the official launch of the second phase of the country's Jawaharlal Nehru National Solar Mission.

Lilly voluntarily terminates Phase II trial for Alzheimer's drug

INDIANAPOLIS, June 16 (UPI) -- U.S. drug maker Eli Lilly and Co. said it stopped its Phase II study of a promising drug to slow Alzheimer's disease over concerns about potential liver damage.

FDA lifts restriction of vaccine trial

ANNAPOLIS, Md., May 30 (UPI) -- The U.S. Food and Drug Administration has ended its hold on PharmAthene's proposed Phase II study of SparVax, a next-generation recombinant anthrax vaccine.

Chemotherapy, no radiation for lymphoma type effective

BETHESDA, Md., April 11 (UPI) -- Patients with a type of lymphoma who received chemotherapy but not radiation therapy to the thorax had excellent outcomes, U.S. researchers say.

CAE gains $128M in military contracts

MONTREAL, April 4 (UPI) -- Canadian modeling and simulation company CAE has received $128 million in contracts for on U.S. and Australian military projects.

New generation oral contraceptive approved

WASHINGTON, March 30 (UPI) -- The U.S. Food and Drug Administration approved Quartette -- levonorgestrel/ethinyl estradiol and ethinyl estradiol -- tablets to prevent pregnancy.

Breast cancer drug promising

NEW YORK, Feb. 27 (UPI) -- An anti-copper drug compound that disables bone marrow cells from receiving migrating cancer tumor cells may curb the spread of cancer, U.S researchers say.
Page 1 of 10
Phase II
Sen. John Rockefeller (D-WV) speaks on Phase II investigation of prewar intelligence at a press conference on Capitol Hill in Washington on November 4, 2005. (UPI/Photo Kevin Dietsch)

Clinical trials are a set of procedures in medical research and drug development that are conducted to allow safety (or more specifically, information about adverse drug reactions and adverse effects of other treatments) and efficacy data to be collected for health interventions (e.g., drugs, diagnostics, devices, therapy protocols). These trials can take place only after satisfactory information has been gathered on the quality of the non-clinical safety, and Health Authority/Ethics Committee approval is granted in the country where the trial is taking place.

Depending on the type of product and the stage of its development, investigators enroll healthy volunteers and/or patients into small pilot studies initially, followed by larger scale studies in patients that often compare the new product with the currently prescribed treatment. As positive safety and efficacy data are gathered, the number of patients is typically increased. Clinical trials can vary in size from a single center in one country to multicenter trials in multiple countries.

Due to the sizable cost a full series of clinical trials may incur, the burden of paying for all the necessary people and services is usually borne by the sponsor who may be a governmental organization, a pharmaceutical, or biotechnology company. Since the diversity of roles may exceed resources of the sponsor, often a clinical trial is managed by an outsourced partner such as a contract research organization or a clinical trials unit in the academic sector.

This article is licensed under the GNU Free Documentation License.
It uses material from the Wikipedia article "Phase II."
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