Osama Hamdan (Arabic: أسامة حمدان, 1965- ) is the top representative of Hamas in Lebanon and is a member of the organization's politburo. He is a member of the Arab National Congress and of the Arab Islamic Conference of the Board of Trustees of the Jerusalem Institute in Lebanon.
Hamdan was born in the Bureij refugee camp in the Gaza Strip to a Palestinian refugee family that fled the village of al-Batani al-Sharqi during the 1948 Arab-Israeli War. He attended high school in Kuwait, graduating in 1982. He then enrolled at the Yarmouk University in Irbid, Jordan where he graduated with a Bachelor's Degree in Chemistry in 1986. While he was at the university, Hamdan became an activist with the Islamic Student Movement. He returned to Kuwait after graduating and worked in the industrial sector until the Gulf War in 1990.
After leaving Kuwait, Hamdan worked at the Hamas office in Tehran as assistant to then Hamas representative Imad Alami from 1992-93. He became Hamas' official representative in Iran in 1994, serving in that post until 1998. While undertaking this post, Hamdan claimed that the "flourishing relations" between Iran and Hamas were at the expense of the once-good relationship between Iran and the Palestinian Liberation Organization (PLO). However, he stated "There is an absence of any proof or evidence of Iranian financial support to Hamas, Islamic Jihad and other Palestinian factions who have established contacts with Iran. It is merely rumours and speculation."