Micheline Anne-Marie Calmy-Rey (born July 8, 1945) is a Swiss politician, member of the Swiss Federal Council since 2002. She is head of the Federal Department of Foreign Affairs (the Swiss foreign minister) and was President of the Confederation in 2007.

Calmy-Rey was born in Sion in the canton of Valais to Charles and Adeline Rey. She received her diploma in 1963 in St. Maurice, and received a DEA degree in political science at the Institut de hautes études internationales (HEI) (Graduate Institute of International Studies) in 1968. In 1966 she married André Calmy. They have two children.

From 1981-1997 Calmy-Rey served as a representative in the Grand Conseil of the canton of Geneva as a member of the Social Democratic Party (PSS/SPS), and served as president of the assembly during 1992-1993. She was president of the Geneva section of the party from 1986-1990 and again from 1993-1997. In 1997, Calmy-Rey was elected to the Conseil d'Etat of Geneva. In 2001 she became head of the Finance Department and president of the Conseil d'Etat.