Matthew J. Bryza is a United States diplomat. He became Deputy Assistant Secretary of State for European and Eurasian Affairs in June 2005.

In this capacity, he is responsible for policy oversight and management of U.S. relations with countries in the Caucasus and Southern Europe. He also leads U.S. efforts to advance peaceful settlements of the separatist conflicts of Abkhazia and South Ossetia in Georgia, and works with the Special Negotiator for Eurasian Conflicts to advance a settlement to the Nagorno-Karabakh conflict. Additionally, Bryza coordinates U.S. energy policy in the regions surrounding the Black and Caspian Seas. He also works with European countries on issues of tolerance, social integration, and Islam.

In April 2001, Bryza joined the National Security Council as Director for Europe and Eurasia, with responsibility for coordinating U.S. policy on Turkey, Greece, Cyprus, the Caucasus, Central Asia, and Caspian energy.