Mark Anderson (born May 26, 1983 in Tulsa, Oklahoma) is a defensive end for the Chicago Bears of the National Football League.

Anderson attended Booker T. Washington High School in Tulsa, Oklahoma and was a student and a letterman in football and basketball. In football, he was an All-Metro selection and was named as a Big 12 Prep pick. Mark Anderson graduated from Booker T. Washington High School in 2001. Anderson recorded 104 tackles and 9 sacks along with 9 receptions and 3 touchdowns during his senior season to help the Hornets to an 11-2 record. In his best game he notched 20 tackles, 3 sacks and 2 blocked punts in 1 game as a senior. He also played basketball.

Anderson attended the University of Alabama (where he became a member of Omega Psi Phi Fraternity, Inc.). He was a four-year letterwinner at Alabama (2001-05) starting 30 of 50 games, including the final 29 of his career, He finished with 141 career tackles, 13.5 sacks, 25 tackles for loss (TFL) (7th all-time at Alabama), 5 forced fumbles, 3 fumble recoveries and 2 passes deflected. He received second-team all-Southeastern Conference accolades as a senior after pacing Alabama with 7.5 sacks and 18 TFLs among 40 tackles while adding 1 forced fumble and 1 blocked field goal in 12 starts.