Margaret Spellings (* Michigan, 1957 - ) was the Secretary of Education under the administration of U.S. President George W. Bush and was previously Assistant to the President for Domestic Policy to President Bush.

She was one of the principal proponents of the 2001 No Child Left Behind Act that aimed at reforming primary and secondary education. In 2005, she convened a Commission on the Future of Higher Education to recommend reform at the post-secondary level. .

Margaret Spellings, born Margaret Dudar on November 30, 1957 in Michigan, moved with her family to Houston when she was in the third grade. Spellings graduated from Sharpstown High School in 1975.