Luis Vizcaíno Arias (born August 6, 1974 in Baní, Dominican Republic) is a Major League Baseball right-handed relief pitcher for the Cleveland Indians.

Vizcaíno was signed by the Oakland Athletics as an amateur free agent in 1994. After gradually working his way through the Athletics minor league system, he made one relief appearance for the A's in 1999, 12 in 2000, and 36 in 2001, but continued to spend significant time in Triple-A. In 2002, he was traded to the Texas Rangers for pitcher Justin Duchscherer, and the Rangers in turn traded him to the Milwaukee Brewers for Jesús Peña.

In his three years with the Brewers, Vizcaíno was a workhorse. After an outstanding 2002 (5-3, 2.99 ERA, 76 appearances), he slumped badly in 2003 (4-3, 6.39 ERA, 75 appearances) before having a bounce-back 2004 campaign (4-4, 3.75 ERA, 73 appearances). Milwaukee then sent him to the Chicago White Sox along with Scott Podsednik and Travis Hinton for Carlos Lee.