Lee Smith (born on November 1, 1944) is an American fiction author who typically incorporates much of her home roots in the Southeastern United States in her works of literature. She has received many writing awards, such as the O. Henry award and the Academy Award For Literature. Her recent book The Last Girls was listed on the New York Times bestseller's list.

Lee Smith was born in 1944 in Grundy, Virginia, a small coal-mining town in the Appalachian Mountains, less than 10 miles from the Kentucky border. The Smith home sat on Main Street, and the Levisa Fork River ran just behind it. Her mother, Virginia, was a college graduate who had come to Grundy to teach school.

Growing up in the Appalachian Mountains of southwestern Virginia, nine-year-old Lee Smith was already writing—and selling, for a nickel apiece—stories about her neighbors in the coal boomtown of Grundy and the nearby isolated "hollers."