Lee Pelekoudas is an executive with the Seattle Mariners Major League Baseball club, most notable for serving as the club's interim general manager from June 16-October 21, 2008. He currently serves as the club's vice president of baseball operations and associate general manager. He is of Greek descent and is the son of former MLB umpire Chris Pelekoudas.

Pelekoudas was selected by the Montreal Expos in the 48th round of the 1969 amateur draft, but attended Arizona State University instead. He has held various front office positions with the Mariners since 1980.

Pelekoudas was the Mariners' associate GM under Bill Bavasi when the latter was dismissed on June 16, 2008, and Pelekoudas was named interim GM by team CEO Howard Lincoln and president Chuck Armstrong. During his tenure as interim GM, several of the field personnel who had become scapegoats for the team's poor performance during the 2008 season were dismissed, including hitting coach Jeff Pentland, field manager John McLaren, first baseman Richie Sexson, and designated hitter José Vidro.