Laura Ziskin (born 3 March 1950) is an American film producer.

Ziskind grew up in the San Fernando Valley in California, in a Jewish American family. She is a 1973 graduate of the University of Southern California USC School of Cinematic Arts. After graduation, Ziskin started out writing for game shows and then became the personal assistant of Jon Peters. She quickly became a development executive, moving into feature films with Jon Peters' production company where she worked on the 1976 remake of A Star Is Born, starring Barbra Streisand. In 1978, she was the associate producer of The Eyes of Laura Mars.

On May 28, 2008, Ziskin, along with Katie Couric, Sherry Lansing, the Entertainment Industry Foundation, the Noreen Fraser Foundation and Ellen Ziffren, announced Stand Up To Cancer. SU2C is an initiative intended to enable cutting-edge research targeting all types of cancer, including breast cancer, prostate cancer, skin cancer, brain cancer, colon cancer, cervical cancer, etc.