Lance Mackey (born 1970) is an American dog musher and dog sled racer from Fairbanks, Alaska, who is a four-time winner of the 1,000-mile Yukon Quest and three-time winner of the Iditarod Trail Sled Dog Race.

In 2007, Lance became the first person to win both the Yukon Quest and Iditarod in the same year. This feat was considered almost impossible by many and is considered one of the most impressive feats by a musher and he was nominated for a 2007 ESPY Award based on his performance. He also won the Veterinarians' Choice award after winning the 2007 Yukon Quest and said "This means more to me than winning this damn race". 2008 was an even better year: Lance won the Tustumena 200, followed by his fourth consecutive Yukon Quest and his second Iditarod. In 2009 he chose not to run the 2009 Yukon Quest but captured his third consecutive Iditarod.

His father Dick Mackey was one of the founders of the Iditarod Trail Sled Dog Race, and won the event by one second over Rick Swenson in 1978. Lance's half-brother Rick Mackey also won the Iditarod Trail Sled Dog Race in 1983. All three of them won the race on their sixth attempt wearing bib number 13.