Jamie Spence (born 26 May 1963 in Tunbridge Wells, Kent) is an English golfer. He turned professional in 1985 and has finished in the top 100 on the European Tour Order of Merit more than a dozen times, with a best placing of tenth in 1992. His two European Tour wins came at the 1992 Canon European Masters and the 2000 Moroccan Open.
In 2003 he succeeded Mark James as the Chairman of The European Tour's Tournament Committee.
Spence also appeared on the Sky TV scientific programme Brainiac: Science Abuse where he took part in "Brainiac Golf" - in which a Brainiac went head to head against Spence. Every time a ball was putted, it set off a fuse, which ignited a caravan filled with a unique gas, such as propane, butane, or pure oxygen, and a different element which coloured the explosive flame.