James Z. Wang (born 1972) is an associate professor of the College of Information Sciences and Technology, the Department of Computer Science and Engineering, and the Integrative Biosciences (IBIOS) Program (Option on Bioinformatics and Genomics) at the Pennsylvania State University. He is also the Vice Director of the Intelligent Information Systems Laboratory and a policy committee member of the I3C infrastructure. He has been a Visiting Professor of the Robotics Institute, Carnegie Mellon University in 2007-2008.

Wang received a summa cum laude Bachelor's degree in Mathematics and Computer Science from University of Minnesota, an M.S. in Mathematics and an M.S. in Computer Science, both from Stanford University, and a Ph.D. degree in Medical Information Sciences from Stanford University's Biomedical Informatics and Database groups.

Wang is the author or coauthor of two monographs and nearly 100 journal articles, book chapters, and refereed conference papers, including one coauthored paper published in Science. His works have been widely cited. For example, SIMPLIcity: Semantics-Sensitive Integrated Matching for Picture Libraries has been received more than 500 citations.