Juan Carlos Romero (born June 4, 1976 in Río Piedras, Puerto Rico) is a Major League Baseball left-handed specialist for the Philadelphia Phillies. He has also played for the Minnesota Twins (1999-2005), Los Angeles Angels of Anaheim (2006), and Boston Red Sox (2007).

Romero played college baseball at the University of Mobile.

Romero was traded by the Twins to the Angels on December 9, 2005, for infielder Alexi Casilla.