Folha de S.Paulo is a Portuguese language newspaper published in São Paulo. It is Brazil's largest in circulation since 2006, and reflects the development of the media in Brazil.. The newspaper has been under the sole ownership of the Brazilian Frias de Oliveira family since 1962.

Folha de S.Paulo played a major role during the many events that occurred in Brazilian society while under the period of the dictatorship. With the return of Freedom of the press, the paper became an important channel for public expression. Folha de S.Paulo also had an important role during the impeachment of President Fernando Collor de Mello in 1992. Today, Folha de S.Paulo is a very important paper nationally, and very influential among the media in Brazil. Folha de S.Paulo presents a broad selection of news, with many in depth articles, on a variety of subjects. It combines this with full color illustrations that provide visual appeal (e.g. graphics, charts, and photographs).

Founded by Olival Costa and Pedro Cunha, Folha de S. Paulo started running its presses on February 19, 1921, under the name of Folha da Noite (literally translated: evening paper). Four years later, a morning edition came out under the name of Folha da Manhã (lit. transl.: morning paper) while its afternoon edition was first released 24 years later. These three separate editions, finally merged in 1960, giving rise to today's Folha de S. Paulo. In 1962, Octavio Frias de Oliveira, a Brazilian media empire mogul, purchased the newspaper. After acquiring several other companies, the Folha group became second only to the Globo conglomerate in Brazil. Eventually the empire was passed on to his children, Luiz and Otavio, who became president and editor respectively. Today, the newspaper has an online editions, titled FolhaOnline hosted on Latin America's largest Internet Service Provider, UOL, which is also part of the Folha conglomerate.