A fifth-inning single by Jose Altuve drove in the go-ahead run Friday and Houston survived 12 strikeouts by Chris Sale to down the Chicago White Sox 2-1.
Ervin Santana frustrated the Astros for seven innings Saturday, holding them to two runs in staking the Kansas City Royals to a 7-2 win over Houston.
Erik Bedard controlled the Angels on one run over seven innings Monday and Houston reeled off a sixth straight win, 2-1 over the Los Angeles Angels.
David Ross hit two of Boston's four home runs Friday in a power display that gave the Red Sox a 7-3 victory over Houston.
Mark Reynolds cracked a go-ahead solo homer in the seventh inning Sunday, powering the Cleveland Indians to a 5-4 win over Houston.
Jed Lowrie went 2-for-4 with four RBI and Nate Freiman bashed a three-run homer during a big first inning Monday in the Oakland Athletics' 11-2 rout of Houston.
Rick Ankiel cracked a three-run homer Sunday and the Houston Astros celebrated their American League debut with an 8-2 victory over Texas.
Rookie Mark Rogers tossed five shutout innings and Carlos Gomez smacked a three-run homer Sunday in the Milwaukee Brewers' 7-0 win over Pittsburgh.
Yadier Molina's two-run double in the fifth inning put St. Louis ahead Saturday and the Cardinals turned back a late Pittsburgh rally for a 5-4 victory.
Clint Barmes launched a grand slam to highlight a nine-run fourth inning Sunday and the Pittsburgh Pirates rallied for an 11-5 victory over San Diego.