Edgar Evans Cayce (March 18, 1877 – January 3, 1945) (pronounced /ˈkeɪsiː/) was an American who was allegedly psychic. He is said to have demonstrated an ability to channel answers to questions on subjects such as health or Atlantis, while in a self-induced trance. Though Cayce considered himself a devout Christian and lived before the emergence of the New Age Movement, some believe he was the founder of the movement and had influence on its teachings.

Cayce became a celebrity toward the end of his life and the publicity given to his prophecies has overshadowed what to him were usually considered the more important parts of his work, such as healing (the vast majority of his readings were given for people who were sick) and theology (Cayce was a lifelong, devout member of the Disciples of Christ). Skeptics challenge the statement that Cayce demonstrated psychic abilities, and traditional Christians also question his unorthodox answers on religious matters (such as reincarnation and Akashic records).

Today there are tens of thousands of Cayce students. Most are located in the United States and Canada, but Edgar Cayce Centers are now found in 25 other countries. The Association for Research and Enlightenment (ARE), headquartered in Virginia Beach, Virginia, is the major organization promoting interest in Cayce.