Notre Dame High School was a Catholic, all-male, non-residential college preparatory school in the Detroit suburb of Harper Woods, Michigan. It was closed in 2005 after more than 50 years due to budget concerns, according to the Archdiocese of Detroit. The school had about 300 students at the time of closure, down from almost 1000 during its peak enrollment levels. It was founded in 1954 and operated by the Marist Fathers and Brothers. Throughout its existence, the school was located next door to Regina High School, a Catholic, all-female school; and Lutheran High School East. Regina moved to Warren, Michigan in 2007, while Lutheran East was closed.

The Archdiocese of Detroit announced in early March 2005 that 18 Detroit-area schools -- including Notre Dame High School -- would be shut down because declining enrollment and an escalating budget deficit. Archdiocese spokesman Richard Laskos called the decision "irrevocable" despite protests from family, students and alumni of the school.

Friends of Notre Dame Incorporated filed a lawsuit to keep the school open, but a Wayne County Circuit Court judge ruled against them.