Derrek Leon Lee (born September 6, 1975 in Sacramento, California) is a Major League Baseball first baseman and team captain for the Chicago Cubs. Prior to being traded to the club in 2004, Lee played with the San Diego Padres (1997) and the Florida Marlins (1998–2003). He bats and throws right-handed.

Lee was born on September 6, 1975. Leon Lee is his father and Leron Lee is his uncle. Each of them played professional baseball in Japan. Derrek often lived in Japan during his summer breaks. Lee was born in Sacramento, California Lee played Little League Baseball at Whitney Little League and graduated from El Camino High School in 1993.

Lee was drafted in the first round (14th overall) of the 1993 Major League Baseball Draft by the San Diego Padres, and made his major league debut on April 28, 1997. Traded to the Florida Marlins a year later, Lee was a member of the 2003 World Series Marlins championship team. Lee won his first Gold Glove during the 2003 championship season and his spectacular grab and unassisted putout on a hard hit Hideki Matsui one-hop line drive snuffed out a Yankees rally and ended Game 5 of the World Series with a Marlins victory. The Marlins went on the win the World Series in Game 6.