DeMarco Murray (born February 12, 1988 in Las Vegas, Nevada) is an American football running back for the Oklahoma Sooners.

DeMarco Murray was coached by David White at Bishop Gorman High School in Las Vegas, Nevada, where he was an all-conference pick three consecutive years. At Gorman, he was a teammate of fellow OU Sooner Ryan Reynolds and current University of Arizona running back Keola Antolin. As a senior in 2005, he rushed for 1,947 yards and 27 touchdowns and also caught 22 passes for 624 yards and 7 touchdowns, earning him all-state honors and the 2005 Sunset Region Offensive Player of the Year award. Murray was invited to play in the U.S. Army All-American Bowl.

Considered one of the top running backs of his class alongside Chris Wells, C. J. Spiller and Michael Goodson, Murray drew offers from Miami (Fl.), Penn State and Texas A&M among others. He chose Oklahoma over Southern California at the U.S. Army All-American Bowl.