Clayton Anthony Rapada (born March 9, 1981 in Portsmouth, Virginia) is a left-handed relief pitcher for the Detroit Tigers.

Rapada started in the Chicago Cubs organization pitching for the Single-A Boise Hawks from 2002–2003. At the beginning of 2003, he was promoted to the Single-A Lansing Lugnuts, where he posted a 5.63 ERA and recorded 24 strikeouts over 24 innings pitched, primarily in relief. During a game that year, Rapada was ejected along with six other players following a brawl with the West Michigan Whitecaps, a Detroit Tigers affiliate. Rapada showed improvement in 2004 for the Lugnuts, going 6–6 with an ERA of 2.33 in 57 appearances.

In 2005, the Cubs moved Rapada up to the Single-A Daytona Cubs, where he went 1–3 with an ERA 3.83 in 27 appearances. 2006 saw Rapada progressing through the Cubs' minor league organization, and he pitched for both the Double-A West Tennessee Diamond Jaxx and the Triple-A Iowa Cubs. Between the two teams, he appeared in 61 games and posted an ERA of 1.59.