Claude B. Humphrey (born June 29, 1944 in Memphis, Tennessee) is a former American football defensive lineman in the National Football League for the Atlanta Falcons and Philadelphia Eagles.
Humphrey was drafted out of Tennessee State University in the first round of the 1968 NFL Draft with the third overall choice by the Falcons. Humphrey was an All-American in 1967.
Humphrey's stellar career included being named First-team All-Pro five times (1971-'74, and 1977), Second- Team All-Pro three times (1969, 1970, 1976), and All-NFC six times (1970-'74, 1977). He was Second-Team All-NFC in 1976 when Humphrey unofficially recorded a career high 15 quarterback sacks. In addition Humphrey was named to the Pro Bowl six times over the span of his career (1970-'74 & 1977).