Chris DeWolfe (born 1966) is one of the creators of MySpace (along with Tom Anderson). He is the former CEO of MySpace. He graduated from the University of Washington in 1988, where he was a member of Beta Theta Pi Fraternity, and the University of Southern California in 1997. He has the sixth account ever made on the website.

On April 22, 2009, News Corp. announced DeWolfe will be stepping down as CEO and will be a strategic adviser to MySpace and serve on the board of MySpace China. Ex Facebook Vet Owen Van Natta will be replacing him.

Chris Dewolfe has been profiled in many major publications such as Fortune and Businessweek.