Carlos Manuel Villanueva Paulino (born November 28, 1983, in Santiago, Dominican Republic) is a right-handed Major League Baseball relief pitcher for the Toronto Blue Jays.
Villanueva was signed by the San Francisco Giants in 2002. He was traded to the Milwaukee Brewers on March 30, 2004, for pitchers Wayne Franklin and Leo Estrella.
As he worked his way through the Brewers' farm system, Villanueva was called up to the Brewers from Double-A Huntsville on May 22, 2006. He made his Major League debut against the Cincinnati Reds on May 23, 2006, pitching a scoreless inning. After being optioned back to the minors, Villanueva was recalled again, making his first career Major League start for the Brewers against the Cincinnati Reds.