Brendan Michael Harris (born August 26, 1980 in (Queensbury, New York) is a Major League Baseball utility infielder who plays for the Minnesota Twins.

Brendan grew up in Queensbury, New York and led the Spartans to the 1998 State Baseball Tournament. He graduated from the College of William and Mary, and was selected in 5th round of the 2001 amateur draft by the Chicago Cubs. Harris made his major-league debut in 2004 with the Cubs, but was sent at the July 31 trade deadline to the Montréal Expos as part of an eight-player, four-team trade that brought Nomar Garciaparra to Chicago. Harris appeared in 20 games for Montréal, batting .160 with one home run and two RBI in 50 at-bats.

In 2005 and 2006, Harris saw limited playing time with the Washington Nationals, with whom he served in the capacity of utility infielder. In July 2006, he was sent by Washington along with Gary Majewski, Bill Bray, Daryl Thompson, and Royce Clayton to the Cincinnati Reds in exchange for Felipe López, Austin Kearns, and Ryan Wagner. Harris was traded to the Tampa Bay Devil Rays in January 2007. He was their starting shortstop for the majority of his breakout 2007 season.