The game is no longer available for purchase on both Goggle Play and Apple's App Store, USA Today reported.
Nguyen took to Twitter Saturday, calling Flappy Bird "a success of mine."
"But it also ruins my simple life. So now I hate it," he wrote.
"I cannot take this anymore," he later wrote.
I am sorry 'Flappy Bird' users, 22 hours from now, I will take 'Flappy Bird' down. I cannot take this anymore.— Dong Nguyen (@dongatory) February 8, 2014
It is not anything related to legal issues. I just cannot keep it anymore.— Dong Nguyen (@dongatory) February 8, 2014
The graphically simple -- and free -- game became a hit in January, topping the iTunes Top Charts.