Woodley, 22, plays Beatrice 'Tris' Prior and James, 29, plays Four in the blockbuster film adaptation of author Veronica Roth's novels.
After having a short conversation with the actors about Woodley's organic ways -- the actress explained she collects her own spring water from local springs -- Kimmel asked the pair if they were nervous about starring in the blockbuster movie.
"We both talked about it, and it's something that you need to really have a bit of a think about, to contemplate how it's going to change your career and your life," said James. "By the same token, you don't know what anything's going to be."
"I think sort of the lack of anonymity would be the most daunting factor in taking on a movie like this," Woodley added. "But you never know! You never know what's going to happen."
Divergent hits theaters on Friday, March 21.
[Jimmy Kimmel Live]