The 44-year-old singer and actress' tribute included three costume changes, a stage full of dancers and a lift from Dancing With the Stars pro Maksim Chmerkovskiy.
"Thank you everyone! Yesterday was beautiful and incredible on so many levels!!!" Lopez tweeted Monday.
"THAT just happened! #AMAs @JLo is EN FUEGO!!!" Chmerkovskiy tweeted.
Known as the "Queen of Salsa," Cruz recorded 23 gold albums and won seven Grammy Awards.