After months of speculation, Kris and Bruce Jenner officially confirmed their separation Tuesday in a statement to their own E! Network.
"We are living separately and we are much happier this way," the couple said of the decision.
"But we will always have much love and respect for each other. Even though we are separated, we will always remain best friends and, as always, our family will remain our number one priority," they added.
In a statement to US Weekly, Kris added: "We ended a marriage, but that's not the end of our friendship. I will always love him, but we are longer a couple in that way."
The Jenners made it through two decades of marriage and hundreds of episodes of reality TV together. They hinted at their impending split over several "Kardashians" episodes last season, in which the 63-year-old Bruce bought his own getaway house in Malibu.
Bruce's son, Brody, admitted Monday that his father and stepmom had been living separately.
“I stay out of their business, but as far as I’m concerned, they haven’t split up,” he said.
Kris wished her husband a happy 22nd anniversary last April.
"Happy Anniversary Bruce!!!! Best 22 years I could ever have imagined...hope the next 22 is even more fabulous...I love you!" she wrote on Instagram.
Celebrity Couples of 2014 [PHOTOS]