"I don't think I'm going to be put back in prison," Knox said. "I think that we're going to win. That's why I'm fighting this fight, that's why I continue to put forth the defensive argument in court."
Knox and her then-boyfriend Raffaele Sollecito were convicted in 2009 of her Kercher, her British roommate in Perugia, Italy. After spending four years in prison, Knox and Sollecito were acquitted on appeal in 2011, and Knox returned to the U.S. The Italian Supreme Court rejected the acquittal and ordered a new trial in March.
The retrial begins September 30 in Florence.
"I look at it as an admission of innocence, to be quite honest," Knox said, of her decision not to return to stand trial. "Besides the fact that there are so many factors that are not allowing me to go back -- financial ones, ones where I'm going to school, ones where I want the court to proceed without distraction. I was imprisoned as an innocent person. It's common sense not to go back."
Knox was convicted and sentenced to 26 years, and Sollecito for 25 years, as prosecutors alleged the murder was part of a sex game gone wrong.
Rudy Guede, a 20-year-old from Côte d'Ivoire, was convicted of the murder and sentenced to 24 years -- later reduced to 16 years -- after his DNA was found on her bed, body and in the bathroom.
Knox's lawyers will represent her at the trial starting next week, and it's unclear if the U.S. would allow her to be extradited to Italy if she's convicted again, as it would violate laws of double jeopardy.