The trailer shows Aniston as a stripper that signs on to smuggle "a smidge of pot" across the Mexican border with Sudeikis' character, whom she meets while giving a lap dance. Together, they create a fake family to avoid suspicion.
The "Friends" star spoke to Chelsea Handler on "Chelsea Lately" on playing a stripper -- while she didn't get fully nude in the film, she wears several sets of lingerie. At some point, she layered three bras atop one another for the role.
Ed Helms, Emma Roberts, Nick Offerman and Will Poulter join the all-star cast. "We're the Millers" opens in theaters on Aug. 9.
Celebrity Families of 2014 [PHOTOS]