The new Levi's Stadium, set to open in Santa Clara, Calif. in 2014, beat out Miami's Dolphins Stadium for the hosting rights for the anniversary game.
Miami also lost out to Houston, which was chosen to host the 2017 game.
The only other Super Bowl hosted by San Francisco was in 1985, held at Stanford Stadium, when the 49ers defeated -- who else? -- the Miami Dolphins, 38 to 16.
The Bay Area bid committee focused their presentation focused on the high-tech features of the new stadium, which will be ticketless and cashless, and offer WiFi access to its 75,000-capacity crowd. The facility will feature sustainable design elements, including a green roof and conservation-minded plumbing.
Team leadership also pledged to donate 25 percent of money generated by the game to help combat local poverty.
“Even before breaking ground in April of 2012, the vision for Levi’s Stadium has always been to build a venue that showcases all that is special about the Bay Area,” said 49ers CEO Jed York. “Innovation, sustainability and fan experience are the pillars of which we designed and constructed this facility."
“We look forward to NFL fans from around the globe enjoying our region and our stadium, the likes of which cannot be found anywhere else in the world.”